The Relationship between home-time, quality of life and costs after ischemic stroke. The impact of the need for mobility aids, home and car modifications on home-time

Purpose: Home-time (the number of days spent at home during the first 3 months after stroke) shows a strong association with the modified Rankin scale (mRS). We studied whether Home-time was also a determinant of quality-of-life and medical care costs after ischemic stroke, and assessed factors delaying discharge home.

What Impact Does Venous Thromboembolism and Bleeding Have on Cancer Patients’ Quality of Life?

Background: Venous thromboembolism (VTE) is common in cancer patients and its treatment is associated with a high risk of recurrent VTE (rVTE) and bleeding. Objectives: To analyze data from the Comparison of Acute Treatments in Cancer Hemostasis (CATCH) trial to describe the impact of rVTE and bleeding events on health-related quality of life.

The impact of cancer-associated thrombosis and treatment related bleedings on patients’ quality of life

This study aimed to capture UK societal utility values for health states associated with T2DM and treatment-related adverse events (AEs) to assess the burden of the disease and common AEs.

Quality of life of patients experiencing cancer-associated thrombosis

Objectives: Cancer patients are at high risk of venous thromboembolism (VTE), provoked by the cancer, chemotherapies or co-morbidities. The CATCH trial investigated the benefits of extended treatment with tinzaparin (LMWH) versus warfarin for the prevention of recurrent VTE events in cancer patients experiencing a VTE.

Health state utilities in non-small cell lung cancer: An international study

Aim: Quality of life weights (utilities) are an important input in economic evaluation and evidence suggests that there can be important differences between countries.

Quality of Life Decrements after Stroke

Objectives: To quantify which factors affect the quality of life valuations (QoL) of patients after stroke. Methods: 569 ischemic stroke patients were recruited into a retrospective, observational study in 10 teaching and regional hospitals across Belgium.

Cost-effectiveness of adjunctive eptifibatide in patients undergoing coronary stenting in Germany

Objective: To determine the cost-effectiveness of adding eptifibatide to the standard treatment for selected high-risk patients undergoing coronary stenting in Germany. Furthermore, to investigate the impact of several extrapolation methods on the results.

Eliciting health state utilities from the general public for severe chronic pain

Objective: There is an absence of data on public preferences for health states (HSs) associated with severe chronic pain. The aim of this study was to develop accurate HS descriptions for severe chronic pain requiring intrathecal (IT) therapy and to derive utility weights that …

The economic value of anti-IgE in severe persistent, IgE-mediated (allergic) asthma patients: adaptation of INNOVATE to Sweden

Background: Severe allergic asthma patients may not be controlled even with guideline recommended care, including inhaled corticosteroids, long-acting beta-2 agonists, theophylline, oral steroids and anti-leukotrienes. They experience exacerbations requiring intensive healthcare use and which may be fatal.

Health state utilities for metastatic breast cancer

The aim of the study was to obtain United Kingdom-based societal preferences for distinct stages of metastatic breast cancer (MBC) and six common toxicities. Health states were developed based on literature review, iterative cycles of interviews and a focus group with clinical experts.